| 產(chǎn)品詳情 |
| Edit |   |
| Product Name | Recombinant Mouse IL-33 (carrier-free) |
| Description | IL-33 belongs to the IL-1 family and is closely related in structure to IL-18 and IL-1b. IL-33, IL-1b, and IL-18 are synthesized as biologically inactive precursor and are cleaved by the enzyme caspase-1 to be secreted as active mature forms. IL-33 stimulates target cells by binding to the IL-1R/TLR superfamily member ST2 and subsequently activates NF-κB and MAPK pathways via identical signalling events to those observed for IL-1b. In addition, IL-33 is a nuclear factor (NF-HEV) abundantly expressed in high endothelial venules from lymphoid organs that associates with chromatin and exhibits transcriptional regulatory properties. |
| Size | 10 μg |
| Concentration | n/a |
| Applications | BA |
| Other Names | NF-HEV, DVS 27 |
| Gene, Accession, CAS # | Gene ID: 77125 |
| Catalog # | 580502 |
| Price | |
| Order / More Info | Recombinant Mouse IL-33 (carrier-free) from BIOLEGEND |
| Product Specific References | PubMed: 20634488,21515798,22079492,23303670 |
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