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產(chǎn)品名稱

Recombinant Mouse IL-34 (carrier-free) from BIOLEGEND

產(chǎn)品貨號

577608

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

500 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Mouse IL-34 (carrier-free)
Description	Mouse IL-34 shares a sequence identity of 71% with human IL-34 on the amino acid level, and the IL-34 gene is syntenic in the human, chimpanzee, rat, and mouse genomes. IL-34 has no apparent consensus structural domain or motif and does not share sequence homology with M-CSF; nevertheless, it binds to the CSFR. These two cytokines are not identical in biological activity and signal activation. IL-34 and CSF show an equivalent ability to support cell growth or survival. However, these cytokines have different ability to induce the production of chemokines (MCP-1 and eotaxin-2) in primary macrophages, the morphological change in TF-1-fms cells, and the migration of J774A.1 cells. The use of monoclonal antibodies against the CSFR suggests a differential domain binding in the receptor to IL-34 and CSF. As a result, different bioactivities and signal activation kinetics/strength are produced for these cytokines.
Size	500 μg
Concentration	n/a
Applications	BA
Other Names	IL34, C16orf77 homolog
Gene, Accession, CAS #	Gene ID: 762577
Catalog #	577608
Price
Order / More Info	Recombinant Mouse IL-34 (carrier-free) from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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