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| Product Name | 8-Nitroguanine |
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| Description | A nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by RNS during inflammation or in vitro; mutagenic and induces G:C to T:A transversion in DNA; stalls human DNA polymerase β and induces a 2:1 preference dA insertion over dC when placed into a primer template as an 8-nitroG:anti-G base pair; levels are increased in the lung tissue of mice with mutant K-Ras(G12V) that developed lung adenocarcinoma and in the lung tissue and peripheral lymphocyte DNA of cigarette smoke-exposed rats; levels are increased in the lung tissue of influenza or Sendai virus-infected mice and in colon epithelial cells of an IBD mouse model |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 8NO2Gua histiocytoma 8Nitroguanine 8NO2 8nitrog 8nitrodg 8-NO2-G 8-nitroG 8-nitroGua 8-nitrodG GC AT antiG 8-NO2-Gua |
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| Gene, Accession, CAS # | CAS: 168701-80-2 |
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| Catalog # | 89295-1 |
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| Price | |
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| Order / More Info | 8-Nitroguanine from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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