| Description | SARS-ACSMS(C) (residues 1051-1076, 1121-1154, 1162-1190) protein.SARS-ACSM contains the C-terminal t section of theSpike protein immunodominant fragments, amino acids:1051-1076, 1121-1154, 1162-1190.SARS-ACSM is purified by proprietary chromatographictechniques.The spike (S) glycoprotein of coronaviruses mediates viralentry into host cells.Spike (S)-glycoprotein of the virus interacts with a cellularreceptor and mediates membrane fusion to allow viralentry into susceptible target cells. It is a type 1 viralfusion protein that characteristically contains two heptadrepeat regions, denoted HR-N and HR-C, that formcoiled-coil structures within the ectodomain of the protein.Previous studies have shown that the two heptad repeatregions can undergo a conformational change from theirnative state to a 6-helix bundle (trimer of dimers), whichmediates fusion of viral and host cell membranes. MW: 37 kDa. Purity >95% by SDS-PAGE |
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