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產品名稱

Granzyme A/GZMA Antibody from BOSTER BIO

產品貨號

PA1588

產品價格

現(xiàn)貨詢價，電話：010-67529703

產品規(guī)格

100ug (sample available)

產品品牌

BOSTER BIO

產品概述

產品詳情

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Antigenic Specificity	Granzyme A/GZMA
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human
Isotype	n/a
Format	immunogen affinity purified
Size	100ug (sample available)
Concentration	500ug/ml.
Applications	IHC, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Rabbit IgG polyclonal antibody for Granzyme A(GZMA) detection. Tested with WB, IHC-P in Human. No cross reactivity with other proteins. Granzyme A is a protein that in humans is encoded by the GZMA gene. Cytolytic T lymphocytes(CTL) and natural killer(NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are though to protect their host by lysing cells bearing on their surface nonself antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. GZMA induces caspase-independent apoptosis in a characteristic manner, except it causes a distinctive form of DNA damage: single-stranded DNA nicking. A target of GZMA is the SET complex, including HMGB2 and ANP32A.
Immunogen	A synthetic peptide corresponding to a sequence in the middle region of human Granzyme A(175-190aa DRKVCNDRNHYNFNPV).
Other Names	Granzyme A;3.4.21.78;CTL tryptase;Cytotoxic T-lymphocyte proteinase 1;Fragmentin-1;Granzyme-1;Hanukkah factor;H factor;HF;GZMA;CTLA3, HFSP;
Gene, Accession #	GZMA, UniProt: P12544
Catalog #	PA1588
Price
Order / More Info	Granzyme A/GZMA Antibody from BOSTER BIO
Product Specific References	n/a
產品資料

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