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| Product Name | TXN, 1-105aa, Human, His tag, E.coli (Bioactivity Validated) |
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| Description | Purity: > 95% by SDS-PAGE Format: Liquid. In Phosphate Buffered Saline pH7.4. SQSTM1 is an adapter protein which binds ubiquitin and regulates signaling cascades through ubiquitination. It may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1 and play a role in titin/TTN downstream signaling in muscle cells. This protein also may be involved in cell differentiation, apoptosis, immune response and regulation of K+ channels. Mutations in the ubiquitin-associated (uBA) domain of the sequestosome 1 protein commonly cause Paget's disease since the uBA is necessary for aggregate sequestration and cell survival. Recombinant SQSTM1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | Enzyme activity |
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| Other Names | Thioredoxin, TRX, TRX1, Thioredoxin JW0871, ECK0879, Thioredoxin reductase, FAD/NAD(P)-binding, TRXR. |
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| Gene, Accession, CAS # | NP 003320 |
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| Catalog # | ATGP0530 |
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| Price | |
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| Order / More Info | TXN, 1-105aa, Human, His tag, E.coli (Bioactivity Validated) from ATGen |
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| Product Specific References | n/a |
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