| 產(chǎn)品詳情 |
| Edit |   |
| Product Name | TAK 960 hydrochloride |
| Description | Potent PLK1 inhibitor (IC50 values are 0.8, 16.9 and 50.2 nM for PLK1, PLK2 and PLK3 respectively). Exhibits >20-fold selectivity for PLK1 over FAK, MLCK and FES, and has minimal activity against a panel of 282 other kinases. Inhibits proliferation of a range of cancer cell lines in vitro and inhibits tumor growth of multiple human cancer cell xenografts in vivo. Orally bioavailable. Purity 98%. MW (observed): 598.06 |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)benzamide hydrochloride |
| Gene, Accession, CAS # | CAS: 1137868-96-2 |
| Catalog # | 5403/10 |
| Price | |
| Order / More Info | TAK 960 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
| 產(chǎn)品資料 |
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