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產(chǎn)品名稱

Recombinant Human RING finger protein 11 (RNF11) from BIOMATIK

產(chǎn)品貨號

RPC24922

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100ug

產(chǎn)品品牌

BIOMATIK

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Human RING finger protein 11 (RNF11)
Description	Purity > 90% as determined by SDS-PAGE. MW: 19.3kDa. Full Length of Mature Protein: 2-154aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Essential component of a ubiquitin-editing protein complex, comprising also TNFAIP3, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Promotes the association of TNFAIP3 to RIPK1 after TNF stimulation. TNFAIP3 deubiquitinates 'Lys-63' polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Recruits STAMBP to the E3 ubiquitin-ligase SMURF2 for ubiquitination, leading to its degradation by the 26S proteasome.
Size	100ug
Concentration	n/a
Applications	RUO
Other Names	n/a
Gene, Accession, CAS #	RNF11, UniProt: Q9Y3C5
Catalog #	RPC24922
Price
Order / More Info	Recombinant Human RING finger protein 11 (RNF11) from BIOMATIK
Product Specific References	n/a
產(chǎn)品資料

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