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產(chǎn)品名稱

Recombinant Human XCL1 (carrier-free) from BIOLEGEND

產(chǎn)品貨號

758006

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Human XCL1 (carrier-free)
Description	XCL1, also known as lymphotactin, is an inflammatory chemokine secreted by T cells and natural killer (NK) cells. Early reports described XCL1 as a mediator of T cell and NK cell migrations, but recent studies suggest a highly specialized role for XCL1 and its receptor XCR1. The XCL1-XCR1 axis has been shown to play an important role in dendritic cell mediated cytotoxic immune response and in the formation of self-tolerance mechanisms through the development of regulatory T cells within the thymus. XCL1 also acts as a conformation-dependent inhibitor of HIV-1. Unlike other chemokines, XCL1 conformation interchanges between conserved chemokine folds and an unrelated dimeric structure under physiological conditions. The XCL1 monomer binds XCR1 with a high affinity, whereas the dimer form binds glycosaminoglycan (GAG) with high affinity, but fails to activate XCR1. Human XCL1 encodes a 114 amino acid precursor protein with a 21 amino acid signal peptide and a single disulfide bond.
Size	100 μg
Concentration	n/a
Applications	BA
Other Names	Lymphotactin, Ltn, ATAC, SCYC1, SCM-1, SCM-1a, lymphotaxin
Gene, Accession, CAS #	Gene ID: 6375
Catalog #	758006
Price
Order / More Info	Recombinant Human XCL1 (carrier-free) from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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