| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | PUMA |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 μg |
| Concentration | 0.5 mg/ml |
| Applications | Western blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PUMA/bbc3 Antibody. PUMA (p53 upregulated modulator of apoptosis) is one of the pro-apoptotic Bcl-2 family members which are also transcriptional targets of p53. PUMA gene encodes two BH3 domain-containing proteins termed PUMA-α and PUMA-β. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis. |
| Immunogen | Synthetic peptide surrounding amino acid 177 of human PUMA |
| Other Names | PUMA/JFY1 ,JFY-1, PUMA, BBC3, bcl-2 binding component 3 |
| Gene, Accession # | Gene ID: 27113, Accession: Q9BXH1 |
| Catalog # | 3339R-100 |
| Price | |
| Order / More Info | PUMA Antibody from BIOVISION, INC. |
| Product Specific References | n/a |
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