| Description | Purity: > 90% by SDS-PAGE Format: Liquid. In 20mM Tris-HCl (pH8.0) containing 10% glycerol,1mM DTT. Nnmt, also known as Nicotinamide N-methyltransferase isoform1, is the family of transferases, specifically those transferring one-carbon group methyltransferases. It is predominantly expressed in the liver, and a lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. Nnmt catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds. Recombinant mouse Nnmt, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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