| Description | Purity: > 95% by SDS - PAGE Format: Liquid. In 50 mM Tris-HCl buffer(pH7.5) 0.2M NaCl, 5mM DTT, 20%glycerol . SET 7/9 is a histone methyltransferase (HMTase) that transfers methyl groups to Lys4 of histone H3, in complex with S-adenosyl-L-methionine (AdoMet). The methylation of lysine residues of histones plays a critical role in the regulation of chromatin structure and gene expression. Acetylation, phosphorylation and methylation of the amino-terminal tails of histone are thought to be involved in the regulation of chromatin structure and function. The enzymes identified in the methylation of specific lysine residue on histones belong to the SET family with just one exception. SET 7/9, unlike most other SET proteins, is exclusively a mono-methylase, Recombinant human SET7/9, was cloned into an E. coli expression vector and was purified to apparent homogeneity by using conventional column chromatography techniques. |
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| Other Names | SET domain-containing protein 7, SETD7, KIAA1717, KMT7, SET7, SET9, SET7/9 Histone methyltransferase, EC 2.1.1.43, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, SET domain-containing protein 7, SET7/9, Lysine N-methyltransferase 7, Histone-lysine N-methyltransferase SETD7, SET domain-containing protein 7 FLJ21193, H3 K4 HMTase, H4 lysine-4 specific, Histone H3 K4 methyltransferase, Histone H3 lysine 4 specific methyltransferase, Histone H4-K4 methyltransferase, Histone lysine N methyltransferase H3 lysine 4 specific SET7, Histone-lysine N-methyltransferase, Lysine methyltransferase, SET 7, SET 7/9, SET 9, SET D7, SET domain containing protein 7, SET domain-containing protein 8, |
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