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| Product Name | PMM2, 1-246aa, Human, His tag, E.coli |
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| Description | Purity: > 95 % by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl. . PMM2, also known as Phosphomannomutase 2, belongs to the eukaryotic PMM family. PMM2 is involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. It catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. Mutations in PMM2 are associated with Congenital disorders of glycosylation (CDG)-Ia, an autosomal recessive disorder characterized by central nervous system dysfunction and multiorgan failure. Recombinant human PMM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Phosphomannomutase 2, CDG1, CDG1a, CDGS, Phosphomannomutase 2 |
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| Gene, Accession, CAS # | NP 000294 |
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| Catalog # | ATGP0727 |
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| Price | |
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| Order / More Info | PMM2, 1-246aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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