| Edit |   |
|---|
| Product Name | Hexokinase 4, 1-465aa, Human, His-tag, E.coli (Bioactivity Validated) |
|---|
| Description | Purity: > 95% by SDS - PAGE Format: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol. Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes-types 1 to 4 hexokinases-have been identified. The enzyme is found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase4 is found in the liver and pancreatic beta-cells, where it is controlled by insulin (activation) and glucagon (inhibition). In pancreatic beta-cells, type IV enzyme acts as a glucose sensor to modify insulin secretion. Hexokinase4 is commonly called `glucokinase'. Recombinant human Hexokinase4, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
|---|
| Size | 50ug, 10ug, |
|---|
| Concentration | n/a |
|---|
| Applications | SDS-PAGE |
|---|
| Other Names | Hexokinase type IV, Glucokinase, GCK |
|---|
| Gene, Accession, CAS # | NP 000153 |
|---|
| Catalog # | ATGP3845 |
|---|
| Price | |
|---|
| Order / More Info | Hexokinase 4, 1-465aa, Human, His-tag, E.coli (Bioactivity Validated) from ATGen |
|---|
| Product Specific References | n/a |
|---|