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| Product Name | HIF1A, 576-785aa, Human, His tag, E.coli |
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| Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 1mM DTT, 10% glycerol . HIF1A, identified as one of the transcription factors, has been found to play an essential role in oxygen homeostasis. This protein is a heterodimer composed of HIF-1beta subunit and one of three subunits(HIF-1A, HIF-2A or HIF-3A). The activation of HIF1A is closely associated with a variety of tumors and oncogenic pathways. HIF1A consists of DNA binding domain(DBD domain), Dimerization domain and C-terminla regulatiory domains, including two transactivation domains(TAD), an oxygen-dependent degradation(ODD) domain, and inhibitory domains. Recombinant human HIF1A(576-785) protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Hypoxia-inducible factor 1-alpha, BHLHE78, MOP1, PASD8, Hypoxia-inducible factor 1-alpha |
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| Gene, Accession, CAS # | NP 001521 |
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| Catalog # | ATGP0647 |
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| Order / More Info | HIF1A, 576-785aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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