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| Product Name | IL33, 109-266aa, Mouse, His tag, E.coli (Bioactivity Validated) |
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| Description | Purity: > 95% by SDS - PAGE Format: Liquid. In Phosphate buffered saline,10% glycerol, 1mM DTT. Interleukin 33 (IL-33) is a 32kDa proinflammatory cytokine that may also regulate gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1. Recombinant mouse IL33 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | Bioactivity |
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| Other Names | Interleukin-33, 230117N10Rik, IL-33, Il-33, Il1f11, Interleukin 33 |
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| Gene, Accession, CAS # | NP 001158196 |
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| Catalog # | ATGP2860 |
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| Order / More Info | IL33, 109-266aa, Mouse, His tag, E.coli (Bioactivity Validated) from ATGen |
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| Product Specific References | n/a |
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