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產(chǎn)品名稱

Recombinant Rat CXCL10/IP-10 (carrier-free) from BIOLEGEND

產(chǎn)品貨號

770901

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

5 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Rat CXCL10/IP-10 (carrier-free)
Description	CXCL10 is an ELR-negative chemokine structurally and functionally related to CXCL9 and CXCL11. ?CXCL10, CXCL9, and CXCL11 are produced and secreted by monocytes, macrophages, fibroblasts, and epithelial cells upon stimulation with proinflammatory cytokines, especially IFNγ. ?CXCL10 chemoattracts CD4, CD8, NK, and NKT cells through the binding to its receptor CXCR3, which is shared with CXCL9 and CXCL11. In addition, CXCL10 inhibits neovascularization in tumors and in wound healing in vivo. Also, CXCL10 has anti-proliferative effects on endothelial cells in vitro, and angiostatic and antitumor effects in vivo. It has been suggested that the anti-proliferative effect of CXCL10 in endothelial cells is CXCR3-independent and that it is mediated through GAG interaction. CXCL10 also possesses antimicrobial activity against E. coli and L. monocytogenes, and both the spore and bacillus forms of B. anthracis. CXCL10 expression is strongly upregulated in many human inflammatory diseases, including rheumatoid arthritis, type I diabetes, multiple sclerosis, atherosclerosis, allograft rejection, and others.
Size	5 μg
Concentration	n/a
Applications	BA
Other Names	Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 10 (SCYB10), INP10, C-X-C Motif Chemokine Ligand 10, 10 KD Interferon Gamma-Induced Protein
Gene, Accession, CAS #	Gene ID: 245920
Catalog #	770901
Price
Order / More Info	Recombinant Rat CXCL10/IP-10 (carrier-free) from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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