| Edit |   |
|---|
| Product Name | Ro 48-8071 |
|---|
| Description | An inhibitor of oxidosqualene cyclase (OSC) that has LDL cholesterol lowering activity; inhibits OSC from human liver microsomes and HepG2 cells with IC50 values of approximately 6.5 and 1.5 nM, respectively |
|---|
| Size | 100 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | monooxidosqualenes cyclases inhibitors OSC cholesterols lowering activity microsomal enzymes catalyzes lanosterol synthetic pathway LDL low-density lipoproteins human livers microsomes HepG2 cells HDL high-desity toxicity CYP3A mRNA proteins hepatocytes cultures atherosclerosis |
|---|
| Gene, Accession, CAS # | CAS: 161582-11-2 |
|---|
| Catalog # | 10006415-100 |
|---|
| Price | |
|---|
| Order / More Info | Ro 48-8071 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|