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產(chǎn)品名稱

SCF, Recombinant, Human from UNITED STATES BIOLOGICAL

產(chǎn)品貨號(hào)

S7973-01A

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

10ug

產(chǎn)品品牌

UNITED STATES BIOLOGICAL

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	SCF, Recombinant, Human
Description	Purity ~95% (SDS-PAGE). Stem cell factor (SCF), also known as c-kit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40kD type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Mature human SCF consists of a 189aa extracellular domain (ECD), a 23aa transmembrane segment, and a 36aa cytoplasmic tail. The ECD shows both N-linked and O-linked glycosylation. Proteolytic cleavage at two alternate sites in the extracellular juxtamembrane region releases a 25kD soluble molecule which is comparable to the only formproduced by Steel-dickie mutant mice. An alternatively spliced isoform of human SCF exists that lacks 28aa that encompass the primary proteolytic recognition site. Within the ECD of the long isoform (correspo
Size	10ug
Concentration	n/a
Applications	n/a
Other Names	SCF, Recombinant, Human (Kit Ligand, Mast Cell Growth Factor, MGF, Stem Cell Factor, c-Kit Ligand, KITLG)
Gene, Accession, CAS #	SwissProt: P21583
Catalog #	S7973-01A
Price
Order / More Info	SCF, Recombinant, Human from UNITED STATES BIOLOGICAL
Product Specific References	n/a
產(chǎn)品資料

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