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產(chǎn)品名稱

SDF-1 beta/CXCL12 (Active) protein from ANTIBODIES-ONLINE GmbH

產(chǎn)品貨號

ABIN988231

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

10 μg

產(chǎn)品品牌

ANTIBODIES-ONLINE GmbH

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	SDF-1 beta/CXCL12 (Active) protein
Description	SDF-1α and SDF-1beta, members of the chemokine α subfamily that lack the ELR domain, were initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. These proteins were subsequently also cloned from a human stromal cell line as cytokines that supported the proliferation of a stromal cell-dependent pre-B-cell line. SDF-1α and SDF-1beta cDNAs encode precursor proteins of 89 and 93 amino acid residues, respectively. Both SDF-1α and SDF-1beta are encoded by a single gene and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the carboxy-terminus of SDF-1beta and absent from SDF-1α. SDF-1/PBSF is highly conserved between species, with only one amino acid substitution between the mature human and mouse proteins. SDF-1/PBSF acts via the chemokine receptor CXCR4 and has been shown to be a chemoattractant for T-lymphocytes, monocytes, pro- and pre- B cells, but not neutrophils. Mice lacking SDF-1 or CXCR4 have been found to have impaired B-lymphopoiesis, myelopoiesis, vascular development, cardiogenesis and abnormal neuronal cell migration and patterning in the central nervous system . Synonym: SDF-1 beta/CXCL12, Mouse. Formulation: Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
Size	10 μg
Concentration	n/a
Applications	n/a
Other Names	n/a
Gene, Accession, CAS #	n/a
Catalog #	ABIN988231
Price
Order / More Info	SDF-1 beta/CXCL12 (Active) protein from ANTIBODIES-ONLINE GmbH
Product Specific References	n/a
產(chǎn)品資料

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