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產(chǎn)品名稱

Recombinant Mouse CCL5 (RANTES) (carrier-free) from BIOLEGEND

產(chǎn)品貨號

594208

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

500 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Mouse CCL5 (RANTES) (carrier-free)
Description	CCL5 is a CC chemokine that directs the migration of leukocytes in immune and inflammatory responses. Increased CCL5 expression has been associated with a wide range of inflammatory disorders and pathologies. It has been shown that CCL5 is highly expressed by breast tumor cells at primary tumor sites and is strongly associated with the progression of breast cancer. CCL5 may contribute to tumor progression by recruiting monocytes into tumor sites, and CCL5 can also stimulate the release of MMP, thereby promoting tumor cell migration. Some studies also show that CCL5 has pro-angiogenesis effects in vivo and in vitro. CCL5 oligomerization and binding to GAGs can induce angiogenic effects through its receptor CCR1 and CCR5. CCL5 is expressed in the early stages of?many viral infections. It has been shown that CCL5 is protective against many viruses including influenza, RSV, HCMV, HCV, and HIV. CCL5 can inhibit HIV infection by competing with the virus for CCR5 binding. CCL5 also has been implicated in the development of asthma, artherosclerosis, and fibrosis.
Size	500 μg
Concentration	n/a
Applications	BA
Other Names	SIS-delta, T-cell specific protein p288, Regulated on Activation, Normal T-expressed and Secreted (RANTES), small inducible cytokine A5
Gene, Accession, CAS #	Gene ID: 20304
Catalog #	594208
Price
Order / More Info	Recombinant Mouse CCL5 (RANTES) (carrier-free) from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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