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產(chǎn)品名稱

LOXO-195 from CAYMAN CHEMICAL COMPANY

產(chǎn)品貨號(hào)

27062-5

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

5 mg

產(chǎn)品品牌

CAYMAN CHEMICAL COMPANY

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Product Name	LOXO-195
Description	An inhibitor of TrkA and TrkC (IC50s = 0.6 and G595R, TrkAG667C, TrkCG623R, and TrkCG696A (IC50s = 2, 9.8, 2.3, and 50 = 1.9 nM); selectively inhibits proliferation of Trk fusion-positive K12, CUTO-3, and MO-91 cell lines (IC50s = ≤5 nM) over Trk fusion-negative cell lines; reduces tumor growth in TrkA-dependent KM12, as well as NIH 3T3 ΔTrkA, ΔTrkA + TrkAG595R, and ΔTrkA + TrkAG667C mouse xenograft models at ≥30 mg/kg
Size	5 mg
Concentration	n/a
Applications	n/a
Other Names	Selitrectinib
Gene, Accession, CAS #	CAS: 2097002-61-2
Catalog #	27062-5
Price
Order / More Info	LOXO-195 from CAYMAN CHEMICAL COMPANY
Product Specific References	n/a
產(chǎn)品資料

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