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產(chǎn)品名稱

Parkin, Human, Control Peptide (RING-type E3 ubiquitin-protein ligase) from UNITED STATES BIOLOGICAL

產(chǎn)品貨號(hào)

P3112-03A

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100ug

產(chǎn)品品牌

UNITED STATES BIOLOGICAL

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Parkin, Human, Control Peptide (RING-type E3 ubiquitin-protein ligase)
Description	Highly purified. A 23 amino acid peptide sequence mapping near the C-terminus of human parkin. Parkinson's is the second most common neurodegenerative disease after Alzheimer's. Parkinson's is characterized by movement disorders-triad of rigidity, resting tremor and bradykinesia. It has been attributed to loss of neurons that produce neurotransmitter dopamine. Recently a new gene, Parkin, has been identified by positional cloning (1) that is responsible for a rare autosomal recessive form of Parkinsonism, AR-JP (2). Human Parkin gene encodes a protein of 465aa (rat 465 aa; mouse 464 aa) with moderate similarity of ubiquitin at the N-terminus and RING-finger motif at the C-terminus. The gene has 12 exons, five of which (3-7) are deleted in AR-JP patients. Some other AR-JP patients have deletions affecting exon 4. Parkin is expressed in many tissues, including brain, heart, testis, and skeletal muscle. In the brain, parkin is expressed in various regions including substantia nigra. Parki
Size	100ug
Concentration	n/a
Applications	n/a
Other Names	n/a
Gene, Accession, CAS #	n/a
Catalog #	P3112-03A
Price
Order / More Info	Parkin, Human, Control Peptide (RING-type E3 ubiquitin-protein ligase) from UNITED STATES BIOLOGICAL
Product Specific References	n/a
產(chǎn)品資料

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