| Description | Glycans are vital components of glycoproteins, glycolipids, and proteoglycans in all domains of life. Glycosylation occurs co- or post-translationally on >50% of eukaryotic proteins resulting in membrane-associated, intracellular, or secreted glycoproteins that are crucial in cellular processes, protein bioactivity and metabolic turnover. Glycoproteins are grouped by the type of carbohydrate and amino acid linkage site. Fucose is found in glycoproteins and glycolipids present in vertebrates, invertebrates, plants, and bacteria. It is often a terminal sugar in glycans participating in cell-cell signaling and migration implicated in physiological and pathological processes such as fertilization, embryogenesis, lymphocyte trafficking, immune r |
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