| 產(chǎn)品詳情 |
| Edit |   |
| Product Name | ML 323 |
| Description | Potent and selective allosteric inhibitor of USP1-UAF1 deubiquitinase complex (IC50 = 76 nM). Exhibits selectivity for USP1-UAF1 over a panel of enzymes, including other deuquitinating enzymes. Inhibits deubiquitination of PCNA and FANCD2 and sensitizes cisplatin-resistant H596 cells to cell death induced by cisplatin (Cat. No. 2251) in vitro. Purity 98%. MW (observed): 384.48 |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 5-Methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-4-pyrimidinamine |
| Gene, Accession, CAS # | CAS: 1572414-83-5 |
| Catalog # | 6435/25 |
| Price | |
| Order / More Info | ML 323 from TOCRIS BIOSCIENCE
|
| Product Specific References | PubMed: 24531842 |
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