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產(chǎn)品名稱

TNF Receptor II/TNFRSF1B Antibody from BOSTER BIO

產(chǎn)品貨號

PB9514

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100ug (sample available)

產(chǎn)品品牌

BOSTER BIO

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	TNF Receptor II/TNFRSF1B
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human, rat
Isotype	n/a
Format	immunogen affinity purified
Size	100ug (sample available)
Concentration	500ug/ml.
Applications	Flow Cytometry, IHC, ICC, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Rabbit IgG polyclonal Picoband? antibody for Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) detection. Tested with WB, IHC-F, ICC, FCM in Human;Rat. No cross reactivity with other proteins. Tumor necrosis factor receptor 2 (TNFR2) is one of receptors of TNF. TNF has proinflammatory and immunosuppressive properties that may segregate at the level of the 2 TNF receptors (TNFRs), TNFR1 and TNFR2. The genes for TNFR1, a 55-kDa protein, and TNFR2, a 70-kDa protein, have been mapped to human chromosomes 12 (12pter-cen) and 1 (1pter-p32), respectively. TNFR2 was induced on glomerular endothelial cells of nephritic kidneys, and TNFR2 expression on intrinsic cells, but not leukocytes, was essential for glomerulonephritis and glomerular complement deposition. TNFR1 promotes systemic immune responses and renal T cell death, while intrinsic cell TNFR2 plays a critical role in complement-dependent tissue injury. Therefore, therapeutic blockade specifically of TNFR2 may be a promising strategy in the treatment of immune-mediated glomerulonephritis.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human TNF Receptor II (288-318aa KKKPLCLQREAKVPHLPADKARGTQGPEQQH), different from the related mouse sequence by eleven amino acids, and from the related rat sequence by ten amino acids.
Other Names	Tumor necrosis factor receptor superfamily member 1B;Tumor necrosis factor receptor 2;TNF-R2;Tumor necrosis factor receptor type II;TNF-RII;TNFR-II;p75;p80 TNF-alpha receptor;CD120b;Etanercept;Tumor necrosis factor receptor superfamily member 1b, membrane form;Tumor necrosis factor-binding protein 2;TBP-2;TBPII;TNFRSF1B;TNFBR, TNFR2;
Gene, Accession #	TNFRSF1B, UniProt: P20333
Catalog #	PB9514
Price
Order / More Info	TNF Receptor II/TNFRSF1B Antibody from BOSTER BIO
Product Specific References	n/a
產(chǎn)品資料

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