| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | ALK |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein A/G purified |
| Size | 100 μg |
| Concentration | n/a |
| Applications | FC, IF, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Monoclonal antibody to detect ALK in human samples. The wild-type anaplastic lymphoma kinase (ALK) protein is a 200kDa transmembrane receptor tyrosine kinase. Its expression is restricted to a few scattered cells in the nervous system (some glial cells and neurons, and a few endothelial cells and pericytes. The hybrid gene, NPM-ALK, created by the t(2;5)(p23;q35) chromosomal translocation encodes part of the nucleolar phosphoprotein, nucleophosmin (NPM), joined to the entire cytoplasmic portion of the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. As a consequence, the ALK gene comes under the control of the NPM promoter, which induces a permanent and ubiquitous transcription of the NPM-ALK hybrid gene, resulting in the producti |
| Immunogen | Recombinant human ALK protein fragment (aa1360-1460) |
| Other Names | ALK Tyrosine Kinase Receptor, ALK/NPM1 fusion gene, Anaplastic lymphoma kinase Ki1, Anaplastic Lymphoma Kinase p80, anaplastic lymphoma receptor tyrosine kinase, CD246, mutant anaplastic lymphoma kinase, NBLST3, Tcrz, TFG/ALK |
| Gene, Accession # | Gene ID: 238, Accession: Q9UM73 |
| Catalog # | A1425-100 |
| Price | |
| Order / More Info | ALK Antibody from BIOVISION, INC. |
| Product Specific References | n/a |
| 產(chǎn)品資料 |
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