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| Product Name | Human CellExp? Granzyme B, human recombinant |
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| Description | Granzyme B (GZMB) also known as Cathepsin G-like 1 (CTSGL1), Cytotoxic T-lymphocyte proteinase 2 (Lymphocyte protease), Fragmentin-2, Granzyme-2, Human lymphocyte protein (HLP), SECT, CGL1, CSPB, CTLA1, GRB, which belongs to the peptidase S1 family. Granzyme subfamily GZMB / CTSGL1 contains 1 peptidase S1 domain. The catalytic activity of Granzyme B is ``Preferential cleavage: -Asp-|-Xaa- >> -Asn-|-Xaa- > -Met-|-Xaa-, -Ser-|-Xaa-``, and is inactivated by the serine protease inhibitor diisopropyl fluorophosphates. GZMB is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. GZMB seems to be linked to activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution an |
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| Size | 10 μg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | GZMB, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT, Fragmentin-2, Granzyme B, Granzyme-2, GRB |
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| Gene, Accession, CAS # | GZMB, Gene ID: 3002, Accession: P10144 |
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| Catalog # | 7233-10 |
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| Price | |
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| Order / More Info | Human CellExp™ Granzyme B, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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