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產(chǎn)品名稱

AEE 788 from TOCRIS BIOSCIENCE

產(chǎn)品貨號(hào)

5318/10

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

10 mg

產(chǎn)品品牌

TOCRIS BIOSCIENCE

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	AEE 788
Description	Potent EGFR and VEGFR inhibitor (IC50 values are 2, 6, 59, 77, 160 and 330 nM for EGFR, ErbB2, VEGFR-1, VEGFR-2, ErbB4 and VEGFR-3 respectively). Also inhibits c-Abl, c-Fms and c-Src (IC50 values are 52, 60 and 61 nM respectively). Inhibits proliferation of EGFR and ErbB2 overexpressing cancer cell lines in vitro. Inhibits tumor xenograft growth and VEGF-induced angiogenesis in mice. Orally active. Purity 98%. MW (observed): 440.58
Size	10 mg
Concentration	n/a
Applications	n/a
Other Names	6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Gene, Accession, CAS #	CAS: 497839-62-0
Catalog #	5318/10
Price
Order / More Info	AEE 788 from TOCRIS BIOSCIENCE
Product Specific References	PubMed: 25823819
產(chǎn)品資料

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