| 產(chǎn)品詳情 |
| Edit |   |
| Product Name | Human IL-21 Synthetic Peptide |
| Description | Human IL-21 Synthetic Peptide. IL-21 is a 17 kDa immunomodulatory cytokine produced mainly by Natural Killer Cells (NKT), T helper (Th) 17 and T follicular helper (TFH) cells. In TFH cells, IL-21 expression leads to autocrine signaling through the IL-21 receptor (IL-21R) and STAT3, which leads to additional transcriptional activation by Bcl6. As with IFN gamma for Th1 and IL-4 for Th2 cells, IL-21 is critical for TFH cell development and effector function. IL-21 plays a role in T cell-dependent B cell differentiation into plasma cells and memory cells, stimulation of IgG production and induction of apoptotic signaling in naive B cells. In Th17 cells, IL-21 expression and autocrine feedback through STAT3, IRF4 and ROR gamma t lead to upregul |
| Size | 50 ug |
| Concentration | n/a |
| Applications | Blocking Assay: Assay Dependent, Control: Assay Dependent |
| Other Names | n/a |
| Gene, Accession, CAS # | Entrez: 59067; Uniprot: Q9HBE4 |
| Catalog # | PEP-0105 |
| Price | |
| Order / More Info | Human IL-21 Synthetic Peptide from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
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