| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | PD-L1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | purified |
| Size | 100 μg |
| Concentration | n/a |
| Applications | Flow Cytometry: 0.5 μg/mL, Immunocytochemistry: 20 μg/mL, Immunofluorescence: 20 μg/mL, Immunohistochemistry: 2.5 μg/mL, Western Blot: 0.5-1 μg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PD-L1 Polyclonal Antibody. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. PDL-1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PDL-1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allograft |
| Immunogen | n/a |
| Other Names | B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, B7 homolog 1, CD274 antigen, PDCD1 ligand 1, programmed cell death 1 ligand 1, programmed death ligand 1 |
| Gene, Accession # | Entrez: 29126, 499342, 60533; Uniprot: Q9EP73, Q9NZQ7 |
| Catalog # | PA5-20343 |
| Price | |
| Order / More Info | PD-L1 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | PubMed: 28196545 |
| 產(chǎn)品資料 |
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