| 產(chǎn)品詳情 |
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| Antigenic Specificity | CTLA4 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1,k |
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| Format | purified |
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| Size | 100ul, 50ul |
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| Concentration | n/a |
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| Applications | ELISA, WB, ICC/IF, Flow cytometry |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CTLA4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that downregulates the immune system. CTLA4 is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Mutations in CTLA4 have been associated with insulin-dependent diabetes mellitus, Graves' disease, Hashimoto's thyroiditis, celiac disease and other autoimmune diseases. |
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| Immunogen | Recombinant human CTLA4 (36-161aa) purified from E. coli |
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| Other Names | Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, CD, CD152, CELIAC3, GRD4, GSE, ICOS, IDDM12 |
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| Gene, Accession # | NP 005205 |
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| Catalog # | ATGA0260 |
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| Price | |
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| Order / More Info | CTLA4 Antibody from ATGen |
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| Product Specific References | n/a |
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