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產(chǎn)品名稱

CTLA-4 Antibody from BIOLEGEND

產(chǎn)品貨號(hào)

525402

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

500 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	CTLA-4
Clone	A3.6B10.G1
Host Species	Mouse
Reactive Species	human
Isotype	IgG2a, κ
Format	purified
Size	500 μg
Concentration	n/a
Applications	ELISA Capture
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Purified anti-human CD152 (CTLA-4). CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein that plays an important regulatory role in the immune system. CTLA-4 is expressed on the surface of helper T cells and transmits an inhibitory signal to T cells. Mutations in the CTLA-4 gene have been associated with various autoimmune diseases, such as systemic lupus erythematosus, insulin-dependent diabetes mellitus, and other autoimmune diseases. An identified novel transcript of the CTLA-4 gene that may represent a native soluble form of CTLA-4 (sCTLA-4) showed that eleven of twenty patients with autoimmune thyroid disease (ATD) had a high concentration of sCTLA-4, whereas only one of thirty apparently healthy volunteers contained measurable levels. sCTLA-4 immunoreactivity was inhibited by its binding to B7.1, suggesting that sCTLA-4 is a functional receptor. sCTLA-4 also plays a role in the initial immune response to infection of immune cells by HIV, along with the CD-1 pathway and others.
Immunogen	Extracellular domain of human CTLA-4 and human IgG1 Fc fusion protein
Other Names	Cytotoxic T-Lymphocyte Antigen 4, (CTLA4)
Gene, Accession #	Gene ID: 1493
Catalog #	525402
Price
Order / More Info	CTLA-4 Antibody from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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