| 產(chǎn)品詳情 |
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| Antigenic Specificity | CTLA-4 |
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| Clone | 1B8 |
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| Host Species | Armenian Hamster |
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| Reactive Species | mouse |
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| Isotype | IgG |
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| Format | fluorescein (FITC) conjugate |
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| Size | 500 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.1-0.2 μg / 1x10^6 cells |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CTLA-4 Monoclonal Antibody (1B8), FITC. CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. |
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| Immunogen | n/a |
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| Other Names | CELIAC3, CTLA-4, GRD4, GSE, ICOS, IDDM12, CD152 isoform, celiac disease 3, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte antigen 4 |
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| Gene, Accession # | Entrez: 12477; Uniprot: P09793 |
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| Catalog # | HMCD15201 |
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| Price | |
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| Order / More Info | CTLA-4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 8596936 |
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