| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | CTLA-4 |
| Clone | A3.4H2.H12 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a, kappa |
| Format | purified |
| Size | 250 ug |
| Concentration | n/a |
| Applications | Flow Cytometry: 1.0 μg/1x10^6 cells |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CTLA-4 Monoclonal Antibody (A3.4H2.H12). CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. |
| Immunogen | n/a |
| Other Names | CD152, CELIAC3, CTLA-4, GRD4, GSE, ICOS, IDDM12, CD152 isoform, celiac disease 3, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated serine esterase-4 |
| Gene, Accession # | Entrez: 1493; Uniprot: P16410 |
| Catalog # | MA5-17731 |
| Price | |
| Order / More Info | CTLA-4 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
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