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產(chǎn)品名稱(chēng)

CD107a Antibody from BIOLEGEND

產(chǎn)品貨號(hào)

328641

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

產(chǎn)品規(guī)格

25 tests

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Antigenic Specificity	CD107a
Clone	H4A3
Host Species	Mouse
Reactive Species	human, African green, baboon, chimpanzee, cynomolgus, pigtailed macaque, rhesus
Isotype	IgG1, κ
Format	PerCP conjugate
Size	25 tests
Concentration	n/a
Applications	Flow Cytometry (FC)
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	PerCP anti-human CD107a (LAMP-1). CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.
Immunogen	Human adult adherent peripheral blood cells
Other Names	LAMP1, LGP-120
Gene, Accession #	Gene ID: 3916
Catalog #	328641
Price
Order / More Info	CD107a Antibody from BIOLEGEND
Product Specific References	PubMed: 21266579,21998199,22718823,24248359
產(chǎn)品資料

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