| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | FOXP3 |
|---|
| Clone | 206D |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, cross-reactivity: cynomolgus, rhesus, baboon, pigtailed macaque |
|---|
| Isotype | IgG1, κ |
|---|
| Format | Pacific Blue? conjugate |
|---|
| Size | 25 tests |
|---|
| Concentration | n/a |
|---|
| Applications | Intracellular Staining for Flow Cytometry (ICFC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Pacific Blue? anti-human FOXP3. FOXP3 is a 50-55 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4+/CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in scurfy mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity. In human, unlike in mouse, two isoforms of FOXP3 have been reported: one (FOXP3) corresponding to the canonical full-length sequence; the other (FOXP3 δ2) lacking exon 2. The 206D antibody recognizes human FOXP3 epitope in the region of amino acids 105-235. |
|---|
| Immunogen | Full-length FOXP3 protein |
|---|
| Other Names | Forkhead box protein P3, Scurfin, JM2, IPEX, Zinc finger protein JM2 |
|---|
| Gene, Accession # | Gene ID: 50943 |
|---|
| Catalog # | 320115 |
|---|
| Price | |
|---|
| Order / More Info | FOXP3 Antibody from BIOLEGEND |
|---|
| Product Specific References | PubMed: 16818678,17577038,17644734,17954571,18156502,18456875,18523152,18641304,18690669,19066178,19240164,19849846,20053943,24838938,25712684 |
|---|
| 產(chǎn)品資料 |
|
国产综合久久,啊灬啊灬快灬高潮了,国产熟女乱子伦露脸视频
|
无码破解成人免费一区,www.黄色网,国内无码
|
奶大灬舒服灬又爽灬高潮,国产精品久久久.,天天日天天色天天干
|
欧美一級黃色A片免費看,喜欢被男人操,91人妻无码精品一区二区
|
91在线无码精品秘 入口不卡,国精品人妻无码一区二区三区牛牛,国产无码福利
|
国产激情直播,91午夜影院,日本亚洲色大成网站www久久
|
天天射一射,极品少妇高潮喷水无码,精品国产乱码
|
色老av,美国式禁忌4,人人天天爽
|
8050网 午夜,亚洲永久无码7777kkk,老女人的逼
|
狂躁少妇XXXX高潮无码,久久久久久免费毛片,精品A片九九九九免费视频
|
|