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產(chǎn)品名稱

SQSTM1/p62 Antibody from BOSTER BIO

產(chǎn)品貨號

PA1955

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100ug (sample available)

產(chǎn)品品牌

BOSTER BIO

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	SQSTM1/p62
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human, mouse, rat (predicted: hamster)
Isotype	n/a
Format	immunogen affinity purified
Size	100ug (sample available)
Concentration	500ug/ml.
Applications	IHC, ICC, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Rabbit IgG polyclonal antibody for Sequestosome-1(SQSTM1) detection. Tested with WB, IHC-P, ICC in Human;Mouse;Rat. No cross reactivity with other proteins. SQSTM1(Sequestosome-1), also known as Ubiquitin-Binding Protein P62 or P62, is a protein that in humans is encoded by the SQSTM1 gene. The Src homology type 2(SH2) domain is a highly conserved motif of about 100 amino acids which mediates protein-protein interactions by binding to phosphotyrosine.p56-lck, a T-cell-specific src family tyrosine kinase with an SH2 domain, is involved in T-cell signal transduction. The International Radiation Hybrid Mapping Consortium mapped the p62 gene to chromosome 5q35. Park et al.(1995) found that the p56-lck SH2 domain binds to p62 at the ser59 of p62 only when that serine is phosphorylated. Joung et al.(1996) expressed epitope-tagged p62 in Hela cells and showed that the expressed protein bound to the lck SH2 domain and that this binding was dependent on the N-terminal 50 amino acids of p62 but not on the tyrosine residue in this region.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human SQSTM1(91-110aa KDDIFRIYIKEKKECRRDHR), different from the related rat and mouse sequences by one amino acid.
Other Names	Sequestosome-1;EBI3-associated protein of 60 kDa;EBIAP;p60;Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa;Ubiquitin-binding protein p62;SQSTM1;ORCA, OSIL;
Gene, Accession #	SQSTM1, UniProt: Q13501
Catalog #	PA1955
Price
Order / More Info	SQSTM1/p62 Antibody from BOSTER BIO
Product Specific References	n/a
產(chǎn)品資料

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