| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | BACE2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | purified |
| Size | 100 μg |
| Concentration | n/a |
| Applications | Immunocytochemistry: 1:10-1:200, Immunofluorescence: 1:10-1:200, Western Blot: 2 μg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | BACE2 Polyclonal Antibody. BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients. |
| Immunogen | n/a |
| Other Names | BACE2, Beta-Site APP-Cleaving Enzyme 2, Aspartyl protease 1, Asp 1, ASP1, Membrane-associated aspartic protease 1, Memapsin-1, Down region aspartic pr |
| Gene, Accession # | Entrez: 25825, 288227, 56175; Uniprot: Q6IE75, Q9JL18, Q9Y5Z0 |
| Catalog # | PA1-753 |
| Price | |
| Order / More Info | BACE2 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | PubMed: 21670066 |
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