| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | CD195 (CCR5) |
| Clone | HEK/1/85a |
| Host Species | Rat |
| Reactive Species | human |
| Isotype | IgG2a, κ |
| Format | Alexa Fluor? 647 conjugate |
| Size | 25 tests |
| Concentration | n/a |
| Applications | Flow Cytometry (FC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Alexa Fluor? 647 anti-human CD195 (CCR5). CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer. |
| Immunogen | CHO cells transfected with human CCR5 |
| Other Names | CCR5, C-C chemokine receptor type 5, HIV-1 fusion co-receptor |
| Gene, Accession # | Gene ID: 1234 |
| Catalog # | 313711 |
| Price | |
| Order / More Info | CD195 (CCR5) Antibody from BIOLEGEND |
| Product Specific References | PubMed: 22848746,24748497,25179963 |
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