| 產品詳情 |
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| Antigenic Specificity | CD195 (CCR5) |
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| Clone | HEK/1/85a |
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| Host Species | Rat |
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| Reactive Species | human |
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| Isotype | IgG2a, κ |
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| Format | Alexa Fluor? 700 conjugate |
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| Size | 25 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alexa Fluor? 700 anti-human CD195 (CCR5). CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer. |
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| Immunogen | CHO cells transfected with human CCR5 |
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| Other Names | CCR5, C-C chemokine receptor type 5, HIV-1 fusion co-receptor |
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| Gene, Accession # | Gene ID: 1234 |
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| Catalog # | 313713 |
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| Price | |
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| Order / More Info | CD195 (CCR5) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 22848746,24748497,25179963 |
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