自慰免费观看,51妺妺嘿嘿午夜成人A片,色婷婷视频在线,北条麻妃一区二区三区四区五区,北条麻妃影音,免费A级毛片无码免费视频首页 ,99热在线观看精品,精品传媒一区二区

<button id="eiezk"><video id="eiezk"></video></button>

產(chǎn)品名稱

Myocilin (MYOC) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH

產(chǎn)品貨號(hào)

ABIN2712098

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

0.25 mg

產(chǎn)品品牌

ANTIBODIES-ONLINE GmbH

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Antigenic Specificity	Myocilin (MYOC) (C-Term)
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human, monkey, mouse, rat
Isotype	n/a
Format	affinity purified
Size	0.25 mg
Concentration	n/a
Applications	Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunoprecipitation (IP),Western Blotting (WB)
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Approximately 4 years ago, the first major (biochemical, molecular biologic, and biologic) insight into primary open-angle glaucoma (POAG) was the presence of mutations in the myocilin (Trabecular meshwork-induced Glucocorticoid Response (Myo/TIGR) gene were related to certain forms of juvenile onset of this disease. Since then, a great deal of work has been done to determine the possible mechanisms by which MYOC/TIGR might cause not only juvenile but also adult-onset primary open-angle glaucoma. Mutation in the myocilin gene is associated with 4% (familial form) of glaucoma cases. Glaucoma is a heterogeneous eye disease and a major cause of blindness worldwide. It has been shown that primary open angle glaucoma (POAG)-associated mutations have been found in the trabecular meshwork inducible glucocorticoid response gene (TIGR), also known as the myocilin gene (MYOC), at the GLC1A locus on chromosome 1q21-q31 (1). Mutation in the TIGR protein coding region is mutated in POAG patients range from 3-4%. Myocilin is found as myocilin-Myocilin complex in the human aqueous humor and these interactions occur between amino acid 117-166 lying with in the leucine zipper motifs. Site directed mutations of the amino acid leucine in the leucine zipper results in disruption of these interactions and mutation (2). The human clone encoding for Myocilin protein of molecular weight of 55 kDa has been isolated and characterized (4). Myocilin, which resembles Myosin, is expressed preferentially in the ciliary rootlets and the basal body of the connecting cilium of the photoreceptor cells. The deduced amino acid sequence of the human myocilin showed significant homologies with non-muscle myosin of dictyostilium discoideum in the N-terminal region and also with olfactomedin of bullfrog in the C-terminal region. Myocilin has a leucine zipper like motif that interacts with other cytoskeletal proteins.Synonyms: GLC1A, MYOC, TIGR, Trabecular meshwork-induced glucocorticoid response protein
Immunogen	Synthetic peptide
Other Names	MYOC\|MGC136645\|zgc:136645\|AI957332\|GLC1A\|TIGR\|GPOA\|JOAG\|JOAG1\|myocilin\|Tigr
Gene, Accession #	Gene ID: 4653,17926,81523
Catalog #	ABIN2712098
Price
Order / More Info	Myocilin (MYOC) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific References	n/a
產(chǎn)品資料

<button id="eiezk"><video id="eiezk"></video></button>