| 產(chǎn)品詳情 |
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| Antigenic Specificity | Sortilin |
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| Clone | W16078A |
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| Host Species | Rat |
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| Reactive Species | human, rat |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-Sortilin. Sortilin was originally purified from human brain tissue and was identified as a new lipoprotein receptor, which was later identified as a multifunctional sorting receptor of the VPS10P-domain receptor family. Although Sortilin is predominately expressed in neurons of the central and the peripheral nervous systems, it is also expressed in metabolic tissues including liver. Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is critical for lipid metabolism, and it has been implicated in lipid disorders. Sortilin is also an APOE receptor implicated in Alzheimer disease. |
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| Immunogen | Human SORT1 recombinant protein (327-638 a.a.) expressed in E. coli. |
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| Other Names | 100 kD NT receptor |
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| Gene, Accession # | Gene ID: 6272 |
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| Catalog # | 852102 |
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| Price | |
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| Order / More Info | Sortilin Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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