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| Product Name | JK 184 |
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| Description | Potent downstream hedgehog (Hh) signaling inhibitor that prevents Gli-dependent transcriptional activity (IC50 = 30 nM). Exhibits antiproliferative activity in a range of cancer cell lines (GI50 = 3 - 21 nM) and in human xenografts in vivo. Inhibits alcohol dehydrogenase 7 (Adh7) (IC50 = 210 nM) and acts as a microtubule depolymerizing agent in vitro. Purity 99%. MW (observed): 350.44 |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolamine |
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| Gene, Accession, CAS # | CAS: 315703-52-7 |
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| Catalog # | 3341/25 |
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| Price | |
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| Order / More Info | JK 184 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 28965853 |
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