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產(chǎn)品名稱

A-419259 from CAYMAN CHEMICAL COMPANY

產(chǎn)品貨號

25605-500

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

500 μg

產(chǎn)品品牌

CAYMAN CHEMICAL COMPANY

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	A-419259
Description	An inhibitor of Src family kinases, including Src, LCK, Lyn, and Hck (IC50s = 9, 50 = 3,000 nM) and PKC (IC50 = >33 μM); inhibits growth of Ph+ K-562 and Meg-01 myeloid leukemia cells (IC50s = 0.1-0.3 and 0.1 μM, respectively), but not Ph- TF-1 and HEL cells; induces apoptosis in K-562 cells in a concentration-dependent manner; inhibits differentiation of murine embryonic stem cells while maintaining pluripotency at 300 nM; reduces the total number of AML cells, as well as AML stem cells, in the bone marrow and spleen of human patient-derived AML mouse xenograft models at 30 mg/kg twice daily
Size	500 μg
Concentration	n/a
Applications	n/a
Other Names	RK-20449
Gene, Accession, CAS #	CAS: 364042-47-7
Catalog #	25605-500
Price
Order / More Info	A-419259 from CAYMAN CHEMICAL COMPANY
Product Specific References	n/a
產(chǎn)品資料

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