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產(chǎn)品名稱

PD-L1/CD274 Antibody from BOSTER BIO

產(chǎn)品貨號

PB9154

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100ug (sample available)

產(chǎn)品品牌

BOSTER BIO

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	PD-L1/CD274
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human
Isotype	n/a
Format	immunogen affinity purified
Size	100ug (sample available)
Concentration	500ug/ml.
Applications	WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Rabbit IgG polyclonal Picoband? antibody for Programmed cell death 1 ligand 1(CD274) detection. Tested with WB in Human. No cross reactivity with other proteins. Programmed death-ligand 1 (PD-L1) also known as CD274 or B7-H1 is a protein that in humans is encoded by the CD274 gene. It is mapped to 9p24.1. PD-L1 is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. It has been concluded that upregulation of PD-L1 on tumor MDCs downregulates T-cell immunity and that PD-L1 blockade may represent an approach for cancer immunotherapy. PD-L1 can provide positive costimulatory signals for innate and adaptive immunity and for protection against intracellular bacterial infection. What's more, It has been found that PD1/PDL1 pathway may be a good target for restoring antitumor immunity in ovarian cancer.
Immunogen	E.coli-derived human PD-L1 recombinant protein (Position: E45-T290). Human PD-L1 shares 69% amino acid (aa) sequence identity with mouse PD-L1.
Other Names	Programmed cell death 1 ligand 1;PD-L1;PDCD1 ligand 1;Programmed death ligand 1;B7 homolog 1;B7-H1;CD274;CD274;B7H1, PDCD1L1, PDCD1LG1, PDL1;
Gene, Accession #	CD274, UniProt: Q9NZQ7
Catalog #	PB9154
Price
Order / More Info	PD-L1/CD274 Antibody from BOSTER BIO
Product Specific References	n/a
產(chǎn)品資料

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