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產(chǎn)品名稱

AML1 / RUNX1 Antibody from LIFESPAN BIOSCIENCES INC.

產(chǎn)品貨號(hào)

LS-C501713

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

LIFESPAN BIOSCIENCES INC.

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	AML1 / RUNX1
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human
Isotype	n/a
Format	Protein G purified
Size	n/a
Concentration	n/a
Applications	ELISA, IF
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	AML1 / RUNX1 Antibody LS-C501713. Specificity: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B-dependent transcriptional activation. Controls the anergy and suppressive function of regulatory T-cells (Treg) by associating with FOXP3. Activates the expression of IL2 and IFNG and down-regulates the expression of TNFRSF18, IL2RA and CTLA4, in conventional T-cells (PubMed:17377532).
Immunogen	Recombinant Human Runt-related transcription factor 1 protein (11-445AA)
Other Names	RUNX1, AMLCR1, Aml1 oncogene, AML1, AML1-EVI-1, CBF-alpha-2, CBFA2, Acute myeloid leukemia 1, EVI-1, PEBP2A2, PEA2-alpha B, AML1-EVI-1 fusion protein, Oncogene AML-1, PEBP2-alpha B, PEBP2aB
Gene, Accession #	RUNX1, Gene ID: 861
Catalog #	LS-C501713
Price
Order / More Info	AML1 / RUNX1 Antibody from LIFESPAN BIOSCIENCES INC.
Product Specific References	n/a
產(chǎn)品資料

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