| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | PDCD1 / CD279 / PD-1 |
| Clone | RMP1-30 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2b |
| Format | affinity purified |
| Size | n/a |
| Concentration | n/a |
| Applications | Flo (1:100 - 1:200) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PDCD1 / CD279 / PD-1 Antibody (clone RMP1-30) LS-C57984. Recognizes mouse CD279, a 55kD cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279. Antibodies produced by clone RMP1-30 do not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells. |
| Immunogen | PD-1 transferred BHK cells. |
| Other Names | PDCD1, CD279, HPD-1, HPD-l, PD1, Protein PD-1, SLEB2, PD-1, CD279 antigen, Programmed cell death 1 |
| Gene, Accession # | PDCD1, Gene ID: 5133 |
| Catalog # | LS-C57984 |
| Price | |
| Order / More Info | PDCD1 / CD279 / PD-1 Antibody from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
| 產(chǎn)品資料 |
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