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產(chǎn)品名稱

Human CD274 Antibody from CREATIVE DIAGNOSTICS

產(chǎn)品貨號

CAB-722RH

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

CREATIVE DIAGNOSTICS

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	Human CD274
Clone	2
Host Species	Rabbit
Reactive Species	human
Isotype	IgG
Format	unconjugated
Size	n/a
Concentration	n/a
Applications	ELISA
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Rabbit Anti-Human CD274 monoclonal antibody for ELISA. Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 family expressed on activated lymphoid cells. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.
Immunogen	Recombinant Protein
Other Names	CD274; CD274 molecule; CD274 antigen , PDCD1LG1, programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; B7 homolog 1; B7 H; B7 H1; B7H1; PD L1; PDL1; CD274 antigen; PDCD1 ligand 1; programmed death ligand 1; B7-H; PD-L1; PDCD1L1; PDCD1LG1; MGC142294;MGC142296;
Gene, Accession #	CD274, Gene ID: 4615, UniProt: Q9NZQ7
Catalog #	CAB-722RH
Price
Order / More Info	Human CD274 Antibody from CREATIVE DIAGNOSTICS
Product Specific References	n/a
產(chǎn)品資料

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