| 產(chǎn)品詳情 |
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| Product Name | Astemizole |
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| Description | Orally active, potent histamine H1 antagonist (IC50 = 4 nM) that displays 20-fold, > 250-fold and > 250-fold selectivity over 5-HT, dopamine and muscarinic acetylcholine receptors respectively. Exhibits antimalarial activity in multidrug resistant strains in vitro (IC50 = 227 - 734 nM). Also potent KV11.1 (hERG) channel blocker (IC50 = 0.9 nM) that displays cardiotoxicity in vivo. Purity 99%. MW (observed): 458.57 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine. Hismanal |
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| Gene, Accession, CAS # | CAS: 68844-77-9 |
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| Catalog # | 3489/50 |
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| Price | |
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| Order / More Info | Astemizole from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23328157 |
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